Sanctification

"Your deeds in protecting the downtrodden have not gone unnoticed, wanderer. A fraction of power from The High Heavens has become available for your plight in the upcoming Season."

- Mechanic description^(src)

Sanctification interface

Sanctification is a gameplay mechanic for Diablo IV. It was introduced in Season of Divine Intervention.

Gameplay

Sanctification is themed around taking angelic power and imbuing it into items. Sanctifying an item has the power to:

• Apply a bonus Legendary power
• Improve an Affix into a Greater Affix
• Add a bonus Affix from a pool of special Sanctification affixes
• Replace an existing Affix with a random Sanctification affix
• Make an item indestructible, preventing it from losing durability

Sanctifying your item makes it unmodifiable, ending that item’s journey. This should be the last upgrade made to an item.

There are a couple different ways to attain this celestial improvement:

• In Pre-Torment difficulties, after defeating a Lesser Evil within one of the game modes they’ve taken over (such as Helltide) the player will have a rare chance to sanctify an item at the Heavenly Anvil. If the player chooses not to use this at the time of invitation, they will not have the option to Sanctify the item again until they receive another divine invitation.
• Players can also obtain Heavenly Sigils, which can be used at will to transport them to the Heavenly Forge to undergo Sanctification. These are only needed to Sanctify items at Ancestral quality. These can only be earned in Torment difficulties.