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A Lo rune is a high rune which can be socketed into equipment in Diablo II: Lord of Destruction. Although Lo is not the rarest rune, it is among the most valuable in ladder play, due to its use in popular ladder-only rune words such as Fortitude and Grief.


Equipment type Effects
Weapon +20% Deadly Strike
Body armor or helm 5% To Maximum Lightning Resist
Shield 5% To Maximum Lightning Resist

Socketing an item with a Lo rune increases the item's level requirement to 59, unless it was already higher.


The Act 2 (H) Good treasure class has a chance to drop a Lo rune, as do higher Good treasure classes.

In single-player, open or ladder games only, the Horadric Cube can transmute two Ohm runes and one normal diamond into one Lo rune.

Rune Words

Lo runes are used in these rune words:

  • Brand 'JahLoMalGul' missile weapon
  • Destruction 'VexLoBerJahKo' polearm or sword
  • Doom 'HelOhmUmLoCham' axe, polearm or hammer
  • Dragon 'SurLoSol' body armor or off-hand armor
  • Fortitude 'ElSolDolLo' weapon or body armor
  • Grief 'EthTirLoMalRal' sword or axe
  • Hand of Justice 'SurChamAmnLo' weapon
  • Ice 'AmnShaelJahLo' missile weapon
  • Phoenix 'VexVexLoJah' weapon or off-hand armor
  • Pride 'ChamSurIoLo' polearm or spear


Lo runes are used in one Horadric Cube recipe.

  • Transmute two Lo runes and a flawless topaz to create one Sur rune. (single-player, open or ladder only)