Curses are hindering effects applied to the player by certain monsters. These are the same types of Curses used by the Necromancer.
Oblivion Knights and the most notable casters of curses, but they are also used by Succubi and Baal.
Curses and Shrine bonuses will overrule each other, this can be annoying when facing hordes of Oblivion Knights right after activating a shrine.
Damaging Skills
Fire — Embers • Eruption • Fire Arrow • Fireball • Fire Bolt • Fire Hit • Firestorm • Fire Wall • Flame Circle • Grenade • Hydra • Incinerate • Incineration Nova • Inferno • Meteor • Mines
Ice — Arctic Blast • Blizzard • Cold Touch • Fire Hit (Cold) • Freezing Charge • Glacial Spike • Hoarfrost
Poison — Poison Bolt • Poison Breath • Poison Cloud • Poison Spit • Poison Spray • Poison Sting • Poison Strike
Lightning — Lightning • Lightning Arrow • Lightning Globe • Lightning Storm • Red Lightning Hose • Shocking Hit • Spark Defense • Thunderbolt
Physical — Bite • Blast Wave • Blow Dart • Charge (Berserk Charge) • Cleave • Corpse Cannon • Destructive Strike • Divebomb • Grab • Ground Spikes • Ground Tentacle • Leap • Javelin • Leech-life Ball • Pummel •Quake • Quill Dart • Slam • Snatch • Spine Dart • Strike • Swipe • Sweep • Whirlwind
Magic — Beam • Blade Beam • Blast • Bomb • Bone Spirit • Hellish Projectile • Nova • Tornado • Torrent • Unholy Bolt
Non-damaging Skills
Indirect Attack — Blood Mana • Curses • Mana Rift • Minion Frenzy • Putrify • Spin Web • Stun • Vortex
Spawning — Bone Prison • Festering Appendages • Lay Egg • Mines • Mystifying Growth • Revive • Summon Minion • Totem
Self-effect — Bone Armor • Burrow •Clone • Fly • Frenzy • Heal • Shell • Teleport • Vile Effigy