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Cultist Blood was a Legendary Crafting Material in Diablo III. It required a Character Level of 1 to use, was account bound, and could be stacked up to 1000 times. It was required for the crafting of the Blood-Magic Edge legendary dagger.

The item had a chance to drop off the unique Dark Cultists of Zealot and Cultist subtypes:

It was recommended to farm it either in Halls of Agony (since the Grand Inquisitor is a guaranteed spawn) or in Alcarnus, due to the small size of that zone.

The dark cultists of the Coven channeled such great amounts of evil magic that their blood became tainted. Unbeknownst to them, this was intended, as they were always meant to be sacrificed to feed their deceitful master, Belial.

Diablo III Crafting Materials

Regular Salvaged and Dropped Materials